Arsenic Exposure and Health Effects Proceedings of the Third International Conference on Arsenic Exposure and Health Effects, July

About this book

The Society of Environmental Geochemistry and Health (SEGH) Third International Conference on Arsenic Exposure and Health Effects was held from July 12-15, 1998 in San Diego, California. Several outstanding papers and posters generated lively discussion and debate not only about scientific issues but also about policy and regulatory issues. While developed countries are considering spending perhaps billions of dollars per year to reach concentrations of 10 micrograms per liter or less, countries like Bangladesh, India and China are trying to deal with much more severe, epidemic scale, arsenic problems with millions of dollars or less. Like its predecessors in 1994 and 1995, The Third SEGH International Conference on Arsenic Exposure and Health Effects (1998) continued the theme of global impact of arsenic. In addition, two new countries with significant arsenic problems, Inner Mongolia and Bangladesh, were represented. The Bangladesh problem could be larger than the one in West Bengal with a possible two-thirds of the population at risk. The conference also featured a session on mechanisms of cancer carcinogenesis. Several scientists presented their work on this important issue which is central to considerations of such questions as the shape of the dose-response curve at low doses. This latter issue was featured in the final session of the conference. Another session that was new and of great interest was on the treatment of victims of chronic arsenic poisoning. This was the most dynamic conference to date and this resulting monograph represents the state-of-the-art in arsenic research on a worldwide basis. It will contribute to the solution of the many problems caused by arsenic exposure throughout the world.

Contents

Chapter headings and selected papers: Occurrence and Exposure. Arsenic in the global environment: looking towards the millenium (I. Thornton). Arsenic in ground water supplies of the United States (A.H. Welch et al.). Hair arsenic as an index of toxicity (J.T. Hindmarsh). Food and Other Exposure Media. Estimating total arsenic exposure in the United States (R.E. Grissom et al.). Arsenic compounds in terrestrial biota (K.J. Irgolic et al.). Dietary exposure to inorganic arsenic (R.A. Schoof et al.). General Overview of Arsenic Risk. Application of the risk assessment approaches in the USEPA proposed cancer guidelines to inorganic arsenic (H.J. Clewell et al.). Health Effects--Non-Cancer. The present situation of chronic arsenism and research in China (G.F. Sun et al.). Groundwater arsenic contamination and suffering of people in Bangladesh (U.K. Chowdhury et al.). Health Effects--Cancer. Cancer risks from arsenic in drinking water: implications for drinking water standards (A.H. Smith et al.). Mechanisms. Arsenite genotoxicity may be mediated by interference with DNA damage-inducible signaling (T.G. Rossman). Metabolism. Variation in human metabolism of arsenic (M. Vahter). Arsenic metabolism after pulmonary exposure (D.E. Carter et al.). Metabolism and toxicity of arsenicals in cultured cells (M. Styblo et al.). Interventions and Treatment. Chronic arsenic toxicity: epidemiology, natural history and treatment (D.N. Guha Mazumder et al.). Treatment and Remediation. Development of an anion exchange process for arsenic removal from water (D.A. Clifford et al.). Subterranean removal of arsenic from groundwater (U. Rott, M. Friedle). Dose Response. Mode of action studies for assessing carcinogenic risks posed by inorganic arsenic (M.E. Andersen et al.).

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