Biochemistry

About this book

Merges a classical organisation and presentation with contemporary insight, information and technology to make modern biochemistry accessible.

Contents

I. THE REALM OF BIOCHEMISTRY. 1. The Scope of Biochemistry. 2. The Matrix of Life: Weak Interactions in an Aqueous Environment. 3. The Energetics of Life. II. MOLECULAR ARCHITECTURE OF LIVING MATTER. 4. Nucleic Acids. 5. Introduction to Proteins: The Primary Level of Protein Structure. 6. The Three- Dimensional Structure of Proteins. 7. Protein Function and Evolution. 8. Proteins in Motion: Contractile Systems and Molecular Motors. 9. Carbohydrates. 10. Lipids, Membranes, and Cellular Transport. III. DYNAMICS OF LIFE: CATALYSIS AND CONTROL OF BIOCHEMICAL REACTIONS. 11. Enzymes: Biological Catalysts. 12. Introduction to Metabolism. IV. DYNAMICS OF LIFE: ENERGY, BIOSYNTHESIS, AND UTILIZATION OF PRECURSORS. 13. Carbohydrate Metabolism I: Anaerobic Processes in Generating Metabolic Energy. 14. Oxidative Processes: Citric Acid Cycle and Pentose Phosphate Pathway. 15. Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism. 16. Carbohydrate Metabolism II: Biosynthesis. 17. Photosynthesis. 18. Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins. 19. Lipid Metabolism II: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids. 20. Metabolism of Nitrogenous Compounds: Principles of Biosynthesis, Utilization, and Turnover. 21. Metabolism of Nitrogenous Compounds: Amino Acids, Porphyrins, and Neurotransmitters. 22. Nucleotide Metabolism. 23. Metabolic Coordination, Metabolic Control, and Signal Transduction V. INFORMATION. 24. Information Copying: Replication. 25. Information Restructuring: Restriction, Repair, Recombination, Rearrangement, and Amplification. 26. Information Readout: Transcription. 27. Information Decoding: Translation. 28. Eukaryotic Genes and Their Expression. Answers to Problems. Glossary. Index.

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Biography

Christopher K. Mathews is Distinguished Professor and Chairman of the Department of Biochemistry and Biophysics at Oregon State University. Dr. Mathews was an Eleanor Roosevelt International Cancer Fellow at the Karolinska Institute in Stockholm in 1984-85 and Tage Erlander Guest Professor at Stockholm University in 1994-95. He has published several books and more than 125 scientific papers dealing with molecular virology, metabolic regulation, nucleotide enzymology, and biochemical genetics. K.E. van Holde is Distinguished Professor Emeritus of Biophysics and Biochemistry at Oregon State University. Dr. van Holde's major research interest is the structure of chromatin; his work resulted in theaward of an American Cancer Society Research Professorship in 1977 and hiselection to the National Academy of Sciences in 1989. He has received Guggenheim, NSF, and EMBO Fellowships and is the author of two books and more than 175 scientific papers. Kevin Ahern is a Senior Instructor in the Department of Biochemistry and Biophysics at Oregon State University, where he pioneered the development of Web-based courses for teaching biochemistry. He is a contributing editor to Science magazine and a columnist for Genetic Engineering News. He has edited two books, Biotechnology Software Reports - Computer Applications for Molecular Biologists and The Biotechnology Software Directory, A Buyer's Guide, and is the founder of DaVinci Press Ink, a scientific software consulting firm. Dr. Ahern's teaching experience includes undergraduate and graduate biochemistry courses.