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Contents
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About this book
Reveals the extraordinary degree to which cell cycle control mechanisms have been conserved through eukaryotic evolution.
Contents
1. Introduction to cell cycle controls; 2. A brief history of the cell cycle; 3. START and the G1-S phase transition in budding yeast; 4. Controlling entry into mitosis in fission yeast; 5. The cdc2 kinase: structure, activation and its role at mitosis in vertebrate cells; 6. Cyclin-dependent kinases: an embarrassment of riches; 7. S Phase and its regulation; 8. Cell cycle progression and cell growth in mammalian cells: kinetic aspects of trasition events; 9. Cancer and the cell cycle; 10. Regulation of the cell cycle during Drosophila development
Customer Reviews
Edited By: C Hutchison and DM Glover
310 pages, 9 illus, 71 figs
A collection of review articles written both by and for participants in the field. The chapters are clearly written and carefully referenced.--American Journal of Human Genetics
"An advanced text that provides a solid conceptual framework for understanding cell-cycle regulation. . . .This book will be useful for a long time."--American Scientist
"Uniformly well written and edited, and highly informative. It is a must for anyone entering this field and of high value generally for libraries and laboratories dealing with modern cell biology and problems of growth and development."--The Quarterly Review of Biology