The 'Advanced Methods' series is intended for advanced undergraduates, postgraduates and established research scientists. Titles in the series are designed to cover current important areas of research in life sciences, and include both theoretical background and detailed protocols. The aim is to give researchers sufficient theory, supported by references, to take the given protocols and adapt them to their particular experimental systems. This book provides a detailed practical guide to cell proliferation and apoptosis detection methods. A novel approach combining both these areas allows important comparisons to be made. Topics covered include all aspects of tissue handling from collection, storage, fixation and processing through to locating and quantifying cells in different stages of the cell cycle. Cell Proliferation and Apoptosis is an essential and comprehensive practical guide to these important and expanding areas.
Ch 1 Introduction to Cell Proliferation and Cell Death. Ch 2. Determination of Cell Number. Ch 3. Nuclear Changes in Dividing Cells. Ch 4. Cell Cycle Proteins. Ch 5. Telomeres and the Control of Cell Division. Ch 6. The Nucleolus and Cell Proliferation. Ch 7. Membrane Alterations in Dying Cells. Ch 8. Morphological Changes in Dying Cells. Ch 9. Caspase Detection and Analysis. Ch 10. Mitochondrial Permeability Changes in Apoptosis. Ch 11. Nuclear Changes in Dying Cells. Ch 12. Flow Cytometric Studies of Cell Death.
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