Books  Animal & General Biology  Biochemistry & Molecular Biology 

Chemical Synthetic Biology

Edited By: Pier Luigi Luisi and Cristiano Chiarabelli

384 pages, illustrations

John Wiley & Sons

Hardback | Mar 2011 | #198233 | ISBN-13: 9780470713976
Availability: Usually dispatched within 4 days Details
NHBS Price: £100.00 $129/€110 approx

About this book

Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, "Chemical Synthetic Biology" shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.


List of Contributors


Part One: Nucleic Acids
1 Searching for Nucleic Acid Alternatives
2 Never-Born RNAs: Versatile Modules for Chemical Synthetic Biology
3 Synthetic Biology, Tinkering Biology, and Artificial Biology: A Perspective from Chemistry
4 Peptide Nucleic Acids (PNAs) as a Tool in Chemical Biology

Part Two: Peptides and Proteins
5 High Solubility of Random-Sequence Proteins Consisting of Five Kinds of Primitive Amino Acids
6 Experimental Approach for Early Evolution of Protein Function
7 Searching for de novo Totally Random Amino Acid Sequences

Part Three: Complex Systems
8 Synthetic Genetic Codes as the Basis of Synthetic Life
9 Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids
10 The Minimal Ribosome
11 Semi-Synthetic Minimal Living Cells

Part Four: General Problems
12 Replicators: Components for Systems Chemistry
13 Dealing with the Outer Reaches of Synthetic Biology Biosafety, Biosecurity, IPR, and Ethical Challenges of Chemical Synthetic Biology
14 The Synthetic Approach in Biology: Epistemological Notes for Synthetic Biology


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