Books  Animal & General Biology  Biochemistry & Molecular Biology 

Cytoskeleton and Small G Proteins

Series: Progress in Molecular and Subcellular Biology Volume: 22

Edited By: P Jeanteur

234 pages, 30 figs


Hardback | Dec 1999 | #104133 | ISBN: 3540648089
Availability: Usually dispatched within 1 week Details
NHBS Price: £193.00 $248/€212 approx

About this book

The internal structure of a cell can be affected by signals in the form of small molecules outside the cell. These changes can then alter the shape or adhesiveness of the cell. This volume centers particularly on one family of cellular proteins which transmit these signals, the Rho Ras-like GTPases, and examines their role in normal cellular processes and development. Also discussed are their roles in cancer formation and microbial pathogenesis.


Rho Familiy Proteins and Regulation of the Actin Cytoskeleton.- Regulation of Cytoskeleton and Cell Adhesion by Rho-Targets.- Rnd Proteins: A New Family of Rho-Related Proteins.- The DH Protein Family, Exchange Factors for Rho-Like GTPases.- RhoGAPs and RhoGDIs: (his)stories of Two Families.- Roles of PAK Family Kinases.- Rac and Cdc42 Effectors.- Small GTPases of the Rho Family and Cell Transformation.- Rho GTP-Binding Proteins As Targets For Microbial Pathogens.- Rho GTPases in Development.

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