DNA Repair and Recombination

About this book

Currently a much discussed topic. This comprehensive book, covering key issues, arose from a Royal Society discussion meeting.

Contents

RecA protein mediates homologous recognition via non-Watson-Crick bonds in base triplets, B.J. Rao and C.M. Radding; the initiation and control of homologous recombination in escherichia coli, Gerald R. Smith et al; formation, translocation and resolution of holliday junctions during homologous genetic recombination, Stephen C. West; structure of the four-way DNA junction and its interaction with proteins, Derek R. Duckett et al; site-specific recombination and circular chromosome segregation, David J. Sherratt et al; steps along the pathway of V(D)J recombination, Martin Gellert and J. Fraser McBlane; regulation and mechanisms of gene amplification, Kathleen A. Smith et al; enzymes acting at strand interruptions in DNA, Tomas Lindahl et al; nucleotide excision repair in the yeast saccharomyces cerevisiae - its relationship to specialized mitotic recombination and RNA polymerase II basal transcription, Errol C. Friedberg et al; proteins that participate in nucleotide excision repair of DNA in mammalian cells, Richard D. Wood; nucleotide excision repair syndromes - molecular basis and clinical symptoms, Dirk Bootsma et al; on the regulation of the p53 tumour suppressor, and its role in the cellular response to DNA damage, David P. Lane et al; mismatch repair, genetic stability and tumour avoidance, Paul Modrich; editing DNA replication and recombination by mismatch repair - from bacterial genetics to mechanisms of predisposition to cancer in humans, M. Radman et al.

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