Books  Animal & General Biology  Genetics 

Human Genetics: Problems and Approaches


By: F Vogel and A G Motulsky

900 pages, 442 figs, 190 tabs


Hardback | Dec 1996 | Edition: 3 | #56711 | ISBN: 3540602909
Availability: Usually dispatched within 1 week Details
NHBS Price: £131.50 $178/€148 approx

About this book

The fourth, completely revised edition of this classical reference and textbook presents a cohesive and up-to-date exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. In the 10 years since the appearance of the third edition, many new insights have emerged for understanding the genetic basis of development and function in human health and disease. Human genetics, with its emphasis on molecular concepts and techniques, has become a key discipline in medicine and the biomedical sciences. The fourth edition has been extensively expanded by new chapters on hot topics such as epigenetics, pharmacogenetics, gene therapy, cloning and genetic epidemiology. In addition, a section giving an overview on the main model organisms (mouse, canine, dog, worm, fly, yeast) used in human genetics research has been introduced. This book will be of interest to human and medical geneticists, scientists in all biomedical sciences, physicians and epidemiologists, as well as to graduate and postgraduate students who desire to learn the fundamentals of this fascinating field.


-History of Human Genetics; -The Human Genome: Chromosomes; -The Human Genome: Genes and DNA; -Formal Genetics of Humans: Linkage Analysis and Gene Clusters; -Formal Genetics of Humans: Multifactorial Inheritance and Common Disease; -Gene Action: Genetic Diseases; - Gene Action: Developmental Genetics; -Mutation: Spontaneous Mutation in Germ Cells; -Mutation: Somatic Mutation, Cancer, and Aging; -Mutation: Induction by Ionizing Radiation and Chemicals; Population Genetics: Description and Dynamics; -Population Genetics: Consanguinity, Genetics Drift; -Human Evolution; -Behavioral Genetics: Research Strategies and Examples; -Behavioral Genetics: Affective Disorders and Schizophrenia; -Behavioral Genetics: Differences Between Poulations; -Genetic Counseling and Prenatal Diagnosis; -Genetic Manipulations and the Biological Future of the Human Species

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