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Molecular Biology of the Toxic Response

By: Alvaro Puga and Kendall B Wallace

Taylor & Francis

Hardback | Dec 1998 | #86562 | ISBN: 1560325925
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About this book

Encouraging the incorporation of molecular biology techniques into the experimental approach to various toxicological problems, the format of the book is two-staged. Each chapter first introduces how various molecular techniques can be successfully applied to solving a specific toxicology question and proceeds to describe the techniques themselves. Also included is a discussion of the benefits and limitations of these techniques . This book will prove of value to practising researchers, but also to graduate students dealing with conceptual issues relating to molecular toxicology.


1. Identification of Genes of Toxicologic Relevance 2. Molecular Indicators of Exposure to Genotoxic Chemicals 3. Uses of Reporter Genes in Toxicology 4. Mechanism of Action of Non-Genotoxic Compounds 5. Signal Transduction in Toxicology 6.Co-evaluation of Toxic and Detoxification Processes. Shamim Ansari, Colgate Palmolive, USA, John Babish, East West Biotech, USA, Michael Battalora, National Institute of Environmental Health Sciences, USA, Shannon Beard, Xenometrix, USA, Klaus Bender,University of Karlsruhe, Germany, May Berenbaum, University of Illinois, USA, Linda Birnbaum, Environmental Protection Agency, USA, Christine Blattner, University of Karlsruhe, Germany, Christopher Bradfield, University of Wisconsin, USA, ChristopherBral, Texas A&M University, USA, Janet Carter, Proctor & Gamble Pharmaceuticals, USA, Lucy Carver, University of Wisconsin, USA, J. Clemons, Michigan State University, USA, Richard ffrench-Constant, University of Wisconsin, USA, J. Christopher Corton,Chemical Industry Institute of Toxicology, USA, Valeria Culotta, John Hopkins University School of Hygiene and Public Health, USA, Valina Dawson, John Hopkins University School of Medicine, USA, Ted Dawson, John Hopkins University School of Medicine, USA,Michael Denison, University of Califonia, USA, Kathleen Dixon, University of Cincinnati, USA, Thomas Doetschman, University of Cincinnati, USA, Kevin Driscoll, Proctor & Gamble Pharmaceuticals, USA, Elaine Faustman, University of Washington, USA, ReneFeyereisen, University of Arizona, USA, John Groopman, John Hopkins University School of Hygiene and Public Health, USA, Christopher Haertel, University of Cincinnati, USA, Oliver Hankinson, UCLA Medical Centre, USA, Diana Hassenbein, Proctor & GamblePharmaceuticals, USA, Peter Herrlich, University of Karlsruhe, Germany, Matin Heur, University of Cincinnati, USA, Larry Hightower, University of Connecticut, USA, Ronald Hines, Wayne State University School of Medicine, USA, Brian Howard, Proctor &Gamble Pharmaceuticals, USA, Nira Ben-Jonathan, University of Cincinnati, USA, Kaname Kawajiri, Saitama Cancer Centre Research Institute, USA, Axel Knebel, University of Karlsruhe, Germany, Sandra Kirchner, University of Washington, USA, Curtis Klaassen,University of Kansas Medical Centre, USA, Walter Koch, Food and Drug Administration, USA, Bernhard Krems, Institute of Microbiology, Germany, Paula Lapinskas, Chemical Industry Institute of Toxicology, USA, George Leikauf, University of Cincinnati, USA,Jie Liu, University of Kansas Medical Centre, USA, Xinfang Ma, East West Biotech, USA, Vicky Valancius-Mangel, University of Cincinnati, USA, Anil Menon, University of Cincinnati, USA, Urs Meyer, University of Basel, Switzerland, Sharon Heath-Pagliuso,University of California, USA, Yoonseong Park, University of Arizona, USA, Weston Porter, Texas A&M University, USA, Markus Probst, UCLA Medical Centre, USA, Penelope Quintana, San Diego State University, USA, Hans Rahmsdorf, Univ

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