Insect transgenesis promises improvements in agriculture, pharmaceuticals and public health. Many important insects can now be routinely transformed with effectors that have useful applications. Agriculture presents the largest market for transgenic insects and has a foundational history of success with sterile insect technique for control of pests including Mediterranean fruit flies and screwworms. Biotechnology will contribute superior markers, suppressible sterility and sex-conversion.
Public health is also seeing transgenic mosquitoes developed which suppress natural populations and are incapable of transmitting disease. Experts in the field will contribute their insights into the latest technology and its applications. Authors will also consider the larger risks, social and economic aspects of transgenic insects whose value must be proven in political, regulatory and public acceptance arenas.
Germline Transformation Technology
Chapter 1. Transposons for insect transformation
Chapter 2. Transposon-based Technologies for Insects
Chapter 3. Sex-, Tissue- and Stage-specific Transgene Expression
Chapter 4. Docking Systems for Site-Directed Transgene Integration
Chapter 5. Inducible and repressible systems for transgene expression
Applications of Transgenic Insects
Chapter 6. Sex ratio manipulation for insect population control
Chapter 7. Conditional Dominant Lethals – RIDL
Chapter 8. Tephritid Fruit Fly Transgenesis and Applications
Chapter 9. Silkworm transgenesis and applications
Chapter 10. Transgenic approaches for sterile insect control of dipteran livestock pests and lepidopteran crop pests
Chapter 11. Anti-pathogen effector molecules: current and future strategies
Chapter 12. Sexual Sterilization of Mosquitoes
Alternative Transgenic Approaches to Modifying Insect Phenotypes
Chapter 13. Paratransgenesis in mosquitoes and other insects: microbial ecology and bacterial genetic considerations
Chapter 14. Asaia paratrangenesis in mosquitoes
Chapter 15. Paratransgenic Control of Chagas Disease
Chapter 16. Tsetse paratransgenesis: a novel strategy for reducing the spread of African trypanosomiases
Considerations for the Release of Transgenic Insects
Chapter 17. RIDL: Modelling Release of Insects Carrying a Dominant Lethal
Chapter 18. Assessing Risk of Transgenic Insects
Chapter 19. Economics of Transgenic Insects for Field Release
Chapter 20. Risk Analysis and the Regulation of Transgenic Insects
Chapter 21. Public acceptability of new insect vector control technologies
Chapter 22. The Cartagena Protocol on the Transboundary Movement of Living Modified Organisms: The Regulation of Trade in Transgenic Organisms under International and European Environmental Law