Edited By: AJ Pawson
368 pages, 42 figs, 14 tabs
Function of SH2 and SH3 domains; structure and function of LIM domains; modular domains of focal adhesion-associated proteins; physiological function of receptor-SH2 interactions; the IRS-signalling system; PDZ domains and the formation of protein networks at the plasma membrane; the mechanisms and function of signalling by the TFG-beta super-family; notch receptors, partners and regulators; signalling through Grb2/ash control of the Ras pathway and cytoskeleton; genetic analysis of sevenless tyrosine kinase signalling in Drosophila.
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