An up-to-date, wide-ranging examination of the function and significance of superantigens in virology, biochemistry, and cell and structural biology as well as immunology. Will interest graduate students and postdoctoral fellows in a wide range of biomedical sciences.
Introduction (B. Huber, E. Palmer); Structural Model of Staphylococcal Enterotoxin A Interaction with MHC Class II Antigens (J.D. Fraser et al.); Superantigens Expresssed by Mouse Mammary Tumor Virus (H. Acha-Orbea); Superantigen Function in Mouse Mammary Tumor Virus-induced Tumorigenesis (S.R. Ross et al.); Polymorphism of TCR VB Regions and Clonal Deletions in Wild Mouse Populations (P.N. Marche et al.); T-Cell Recognition of Superantigens: Role of Non-VB TCR Elements and MHC Molecules (M.A. Blackman et al.); MTV-encoded Superantigen Expression in B Lymphoma Cells on SJL Mice as a Stimulus for Reversed Immun-ological Surveillance (V.K. Tsiagbe et al.); Superantigenicity of Rabies Virus Nucleocapsid in Humans and Mice (M. Lafon et al.); Superantigens and the Patho-genesis of Viral Diseases (H. Soudeyns et al.); HIV-1 Replication in T Cells Dependent on TCR VB Expression (D.N. Posnett et al.)