African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30 percent of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America. "The African Trypanosomes", volume one of "World Class Parasites", is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.
'[...] this book is not just attractive for researchers working on African trypanosomiasis, it will also be a very useful addition to the protozoological section of a library for other researchers and students.' European Journal of Protistology, 38 (2002)
Preface. African Trypanosomiasis. Failure of Science and Public Health; D. Molyneux. The Programme Against African Trypanosomiasis Information System (PAATIS); M. Gilbert, et al. Effects of Climate, Human Population and Socio-Economic Changes on Tsetse-Transmitted Trypanosomiasis to 2050; J.J. McDermott, et al. Tsetse Vector Based Strategies for Control of African Trypanosomiasis; S. Aksoy. Diagnosis of Human and Animal African Trypanosomiasis; P. Buscher. Chemotherapy of African Trypanosomiasis; J.R. Seed, D.W. Boykin. Immunobiology of African Trypanosomiasis -- New Paradigms, Newer Questions; J.M. Mansfield, et al. Identifying the Mechanisms of Trypanotolerance in Cattle; J. Naessens, et al. Trypanosome Factors Controlling Population Size and Differentiation Status; N.B. Murphy, T. Olijhoek. The Endocytic Machinery of Bloodstream Stage African Trypanosomes; D. Nolan, et al. The Genome of The African Trypanosome; J.E. Donelson. Towards A Trypanosomiasis Vaccine; S.J. Black, et al. Epilogue. Index.
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