Provides a unified theory that addresses the problem of the origin and maintenance of genetic variation in natural populations.
"John Gillespie has thought harder than anyone else about the subtleties of the ways in which natural selection can bring about variation and evolution at the molecular level, and he has an enviable command of the theoretical and empirical literature on molecular evolution. [His book] deserves the careful attention of everyone interested in this field....Well written and informative." --Science
"I like this book, and it is valuable to have many elements of the debate under one cover....This work will begin to counter the influence that defenders of the neutral theory have enjoyed over the past decade....A timely contribution which will promote interest in the study of adaptation at the molecular level." --Nature
"Presents a unified theory that tackles the important current problem of the origin and maintenance of the genetic variation found in natural populations. Consideration of the great advances made in the discipline of population genetics makes this of interest to many
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