Books  Animal & General Biology  Genetics 

The Hierarchical Genome and Differentiation Waves: Novel Unification of Development, Genetics and Evolution

Series: Series in Mathematical Biology and Medicine Volume: 3

By: Richard Gordon

1836 pages, Figs (2 Vol Set)

World Scientific Publishing

Hardback | Aug 1999 | #59737 | ISBN: 9810222688
Availability: Usually dispatched within 6 days Details
NHBS Price: £98.99 $127/€107 approx

About this book

Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms, including their evolution and genetics.


Part 1 Introduction: consider a spherical cow; the epigenetic problem; primary neural induction and the organizer. Part 2 Theory of the cell state splitter causing primary neural induction: the intra-cellular mechanics of the cell state splitter yields ectodermal differentiation; the mechanics of cell-cell interactions yields tissues. Part 3 Development and genetics: the general cell state splitter; differentiation trees; development and evolution; evolution of cell state and tissue splitting; the secondary importance of embryonic induction. Part 4 Macroevolution: redefining microevolution and macroevolution; possible DNA mechanisms for macroevolutionary change of differentiation trees. Part 5 Old problems seen via differentiation trees: "ontogeny recapitulates phylogeny" revisited via differentiation trees; neutralist theory. Part 6 A cornucopia of differentiation waves: summary of waves observed in the axolotl; differentiation waves in plant meristems. Part 7 Conclusion: the logic of evolution; is evolution progressive?. (Part Contents).

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