Fungal Genomics is divided into four sections, the first of which, Genome...
270 pages, 37 illus, 6 in colour
Through the integration of bioinformatic, genetic, transcriptomic, proteomic, metabolomic, phenomic and other massive datasets, genomics is revealing exciting new insights into fungal cell biology. The central theme of this volume is the strong impact that genomics is having upon our understanding of fungal biology, across a wide range of species, including model yeasts (such as Saccharomyces cerevisiae and Schizosaccharomyces pombe), filamentous fungi (such as Neurospora crassa and Aspergillus nidulans) and pathogenic fungi (such as Magnaporthe grisae, Candida albicans, Cryptococcus neoformans and Histoplasma capsulatum). World-renowned scientists address the following topics in these fungi: systems biology and evolution, circadian rhythms, apoptosis and stress responses, secretion, and environmental signalling networks. Particular emphasis is placed on fungal pathogenicity. Various genomic technologies are discussed, including genome-wide sequence comparisons, transcript profiling, proteomics, metabolomics and bioinformatics.
From the reviews: "The book is split into three sections. ! this is a very interesting book and will find a space on my bookshelf. ! I am sure that I will be returning to it for initial information on a range of topics: the figures and references (including website resources) are particularly good." (A. Buddie, Bibliography of Systematic Mycology, Vol. 12 (3), 2007)
Metabolomics and Systems Biology in Saccharomyces cerevisiae.- Genome Evolution in Hemiascomycete Yeasts.- Investigating the Evolution of Fungal Virulence by Functional Genomics.- Circadian Rhythms, Photobiology and Functional Genomics in Neurospora.- Genomics of Protein Secretion and Hyphal Growth in Aspergillus.- The Genomics of Stress Response in Fission Yeast.- Programmed Cell Death and Apoptosis in Fungi.- Genomic Analysis of Cellular Morphology in Candida albicans.- Postgenomic Approaches to Analyse Candida albicans Pathogenicity.- Integration of Metabolism with Virulence in Candida albicans.- Regulators of Candida glabrata Pathogenicity.- Using Genomics to Study the Life Cycle of Histoplasma capsulatum.- Cryptococcus neoformans Pathogenicity.
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