The Tambopata-Candamo region is strategically located in the heart of a potential conservation `mega-corridor' that would biologically link conservation units in Peru with those of Bolivia. This corridor offers the best hope of retaining viable populations of animals such as giant otters and other species with large space requirements. The area also has a highly diverse flora and fauna with many endemic species. This publication describes the biological importance of Tambopata-Candamo and makes recommendations regarding the conservation and development of the region.