Theoretical and Computational Methods in Genome Research

Contents

Evaluating the Statistical Significance of Multiple Distinct Local Alignments; S.F. Altscul. Hidden Markov Models for Human Genes: Periodic Patterns in Exon Sequence; S. Brunak. Identification of Muscle-Specific Transcriptional Regulatory Regions; J.W. Fickett. A Systematic Analysis of Gene Functions by the Metabolic Pathway Database; M. Kanehisa. Polymer Dynamics of DNA, Chromatin and Chromosomes; J. Langowski. Is Whole Human Genome Sequencing Feasible?; E.W. Myers. Sequence patterns Diagnostic of Structure and Function; T.F. Smith. Recognizing Functional Domains in Biological Sequences; G.D. Stormo. Stochastic Modelling in Molecular Genetics; P. Tautu. The Integrated Genomic Database (IGD): Enhancing the Productivity of Gene Mapping Projects; S.P. Bryant. Error Analysis of Genetic Linkage Data; R. Cottingham. Managing Accelerating Data Growth in the Genome Database; K.H. Fasman. Advances in Statistical Methods for Linkage Analysis; D.E. Weeks. Exploring Heterogeneous Molecular Biology Databases in the Context of the Object-Protocol Model; V.M. Markowitz. Comprehensive Genome Information Systems; O. Ritter. Visualizing the Genome; D.B. Searls. Data Management for Ligand-Based Drug Design; K. Aberer. 7 Additional Articles. Index.

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