Series: Developmental and Cell Biology Series Volume: 36
By: Nicole Le Douarin(Author), Chaya Kalchem(Author), Lewis Wolpert(Foreword By)
445 pages, b/w plates, illustrations, tables
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. The Neural Crest is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
"Any developmental biologist will enjoy this book [...] the questions and the experimental approaches will be appreciated by all."
Foreword Lewis Wolpert
Preface N. Le Douarin
1. Methods for identifying neural crest cells and their derivatives
2. The migration of neural crest cells
3. The neural crest: a source of mesenchymal cells
4. From the neural crest to the ganglia of the peripheral nervous system: the sensory ganglia
5. The autonomic nervous system and the endocrine cells of neural crest origin
6. The neural crest: source of pigment cells
7. Cell lineage segregation during neural crest ontogeny
Concluding remarks and perspectives
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