Books  Animal & General Biology  Biochemistry & Molecular Biology 

Cell Growth: Control of Cell Size

Edited By: M Hall, M Raff and G Thomas

652 pages, Tabs, figs

Cold Spring Harbor Laboratory Press

Paperback | May 2004 | #149848 | ISBN: 0879696729
Availability: Usually dispatched within 6 days Details
NHBS Price: £11.50 $14/€14 approx

About this book

Recent breakthroughs in the field of cell growth, particularly in the control of cell size, are reviewed by experts in the three major divisions of the field: growth of individual cells, growth of organs, and regulation of cell growth in the contexts of development and cell division. This book is an introductory overview of the field and should be adaptable as a textbook.

"Collectively, the different chapters cover a wide range of topics that will be of particular interest to cell, developmental and evolutionary biologists alike...The book's multi-disciplinary nature will make it an excellent reference for many scientists. Cell Growth, like many titles from the Cold Spring Harbor monograph series, should stand the test of time and serve as a solid foundation for this ever-expanding field" Nature

Collectively, the different chapters cover a wide range of topics that will be of particular interest to cell, developmental and evolutionary biologists alike...The book's multi-disciplinary nature will make it an excellent reference for many scientists. Cell Growth, like many titles from the Cold Spring Harbor monograph series, should stand the test of time and serve as a solid foundation for this ever-expanding field. Nature The book begins with an excellent, although brief, foreword on the principles of cell-size regulation and a first chapter-How Metazoans Reach Their Full Size: The Natural History of Bigness-that discusses key concepts connecting cell growth to organism size. Together, they provide a pleasing intellectual framework for the entire book, and each chapter would also be appropriate as teaching material in a graduate student class. The rest of the book consists of chapters covering more specialized topics... Cell Growth: Control of Cell Size is an authoritative and detailed book on growth regulation. Nature Cell Biology The publication of this book coincides with the onset of a new era in growth studies, and it should be of great use for helping students and researchers appreciate growth as a regulated process playing key roles in many developmental, physiological, and pathological events. Developmental Cell


Contents

Building a body - interleaving of growth, patterning, and cell proliferation during multicellular development; linkages between cell growth and cell cycle progression during development; co-ordination of cell growth and cell cycle progression in proliferating mammalian cells; integration of growth with the cell cycle; TOR signaling in yeast: temporal and spatial control of cell growth; TOR and insulin signaling in drosophila; mTOR and control of cell growth in response to nutrients; IGF I receptor signaling in cell growth; S6 Kinase and cell growth; control of cell growth via translation initiation; synaptic growth, synaptic maintenance, and long-term memory storage; the control of synaptic function by local protein synthesis and degradation; forging the factory: ribosome synthesis and growth control in budding yeast; control of rRNA and tRNA production is closely tied to cell growth and biosynthetic capacity; cellular recycling system: molecular mechanism of autophagy; plant cell growth in the solid state; genetic analysis of growth regulation in the drosophila eye; lymphocyte growth; control of skeletal muscle mass; the mechanism of control of the heart size in mammals; regulation of cell growth in the endocrine pancreas.

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