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British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published eight times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

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Academic & Professional Books  Reference  Data Analysis & Modelling  Data Analysis & Statistics

Statistical Genomics of Complex Traits Linkage, Disequilibrium and QTL

Handbook / Manual
By: Rongling Wu, Changxing Ma and George Casella
365 pages
Publisher: Springer Nature
Statistical Genomics of Complex Traits
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  • Statistical Genomics of Complex Traits ISBN: 9781441919120 Paperback Nov 2010 Not in stock: Usually dispatched within 1-2 weeks
    £136.00
    #194121
  • Statistical Genomics of Complex Traits ISBN: 9780387203348 Hardback Jul 2007 Not in stock: Usually dispatched within 1-2 weeks
    £179.99
    #165822
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About this book

This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.

Contents

Basic Genetics.- Basic Statistics.- Linkage Analysis and Map Construction.- A General Model for Linkage Analysis in Controlled Crosses.- Linkage Analysis with Recombinant Inbred Lines.- Linkage Analysis for Distorted and Misclassified Markers.- Special Considerations in Linkage Analysis.- The Structure of QTL Mapping.- Marker Analysis of Phenotypes.- Regression-Based Interval Mapping.- Maximum Likelihood Interval Mapping.- Threshold and Precision Analysis.- Composite QTL Mapping.- QTL Mapping in Outbred Pedigrees.

Customer Reviews

Handbook / Manual
By: Rongling Wu, Changxing Ma and George Casella
365 pages
Publisher: Springer Nature
Media reviews

From the Reviews: "[I]t is a big help and guidance in the field of statistical developments for genetic mapping, synthesised all in one volume helping to build a bridge between genetics and statistics." (Lutz Bunger, Genetic Research, 89, 2007) "...[T]his is an ideal book for a young researcher looking for an exciting and developing field to get into." (International Statistics Review, April 2008)

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