Drosophila: A Toolbox for the Study of Neurodegenerative Disease

About this book

Molecular genetics uses Drosophila as a model organism for research purposes. Drosophila: A Toolbox for the Study of Neurodegenerative Disease gives an overview of the ways in which Drosophila are used for research, including some of the experiments and findings, and common models of diseases, especially neurodegenerative ones, that affect humans that have been based heavily on Drosophila research.

Contents

Preface
1. Modelling Neurodegenerative Diseases in Drosophila
2. Drosophila Genetics for the Analysis of Neurobiological Disease
3. Using Drosophila Models to Unravel Pathogenic Mechanisms That Underlie Neurodegeneration in Tauopathies
4. Modelling Cell and Isoform Type Specificity of Tauopathies in Drosophila
5. Using a Drosophila Model of Alzheimer's Disease
6. Amyloid Peptides and Ion Channel Function in Drosophila Models of Alzheimer's Disease
7. Genetic Models of Parkinson's Disease: Mechanisms and Therapies
8. Modelling Lyosomal Storage Disease in Drosophila
9. Drosophila melanogaster in the Study of Epilepsy
10. Hereditary Spastic Paraplegia Genes in Drosophila: Dissecting Their Roles in Axonal Degeneration and Intracellular Traffic
11. Triplet Repeat Diseases - Role of Fly Models in Understanding Disease Mechanisms and Designing Possible Therapies

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