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Exploring mutations through text, illustrations, examples and animations covering:
Significance of mutations.
Types of gene and chromosome mutations.
Origin of mutations
Rates and repair of mutations
Consequences of mutations
Protein sorting and transport
Mutations and evolution
Mutations - changes to the genetic make-up of an organism - are hugely important. Some of them are deleterious, in that they cause abnormalities and diseases. But most of them turn out to be neutral and some even have beneficial effects. In this way, mutations are ultimately responsible for all the genetic variation that we see in populations of humans and other species. And it is this genetic variation that allows evolutionary changes to take place. On top of all this, mutations enable us to study the genes themselves, to locate them, to study their inheritance, to isolate them, to correct them, to use them. Mutations, therefore, underpin virtually all aspects of genetics! This comprehensive program introduces the types, origins and consequences of both gene (DNA) and chromosome mutations. It then elaborates their short term effects (such as in cancer, inborn errors and disease) and their long term (evolutionary) importance. A diagnostic test with feedback helps students to grasp fundamental concepts. A large number of photographs, illustrations and animations, from humans, animals and plants, support the authoritative coverage and make it relevant for all students of biology.
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