This first textbook of its kind provides an ideal introduction to the field for students of biology and bioinformatics. Carefully designed study exercises - with corresponding answers - offer excellent support for those preparing for exams in these subjects, and help introduce the more technical aspects of the topic. In particular the text focuses on a network-based approach to the study of cellular systems.
A"This volume contains succinct, yet clear, descriptions of each of these topics and is best suited for readers who are delving into these concepts for the first time.A"( The Quarterly Review of Biology , 2009)
NETWORKS OF BIOLOGICAL CELLS BIOCHEMICAL PATHWAYS PROPERTIES OF MATHEMATICAL GRAPHS PROTEIN-PROTEIN INTERACTION NETWORKS - PAIRWISE CONNECTIVITY PROTEIN-PROTEIN INTERACTION NETWORKS - STRUCTURAL HIERARCHIES GENE REGULATORY NETWORKS LINEAR ALGEBRA PRIMER METABOLIC NETWORKS SPATIAL RECONSTRUCTION PROTEIN COMPLEXES KINETIC MODELLING OF CELLUAR PROCESSES INTEGRATED NETWORKS
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Volkhard Helms has been Professor of Bioinformatics in the Center of Bioinformatics, Saarland University since 2003, where he heads the bioinformatics department. He worked for his PhD in the European Molecular Biology Laboratory in Heidelberg and carried out post-doctoral work at UC San Diego. He then went on to lead a research group in theoretical biophysics at the Max Plank Institute of Biophysics in Frankfurt. In 2001 he was selected as an EMBO Young Investigator, and since 2000 he has been a member of the "Faculty of 1000". His work focuses on experimental and computational approaches to the study of protein-protein interactions.