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Laboratory Biosecurity Handbook

Handbook / Manual

By: Reynolds M Salerno and Jennifer Gaudioso

188 pages, Figs, tabs

CRC Press

Hardback | Jun 2007 | #169802 | ISBN-13: 9780849364754
Availability: Usually dispatched within 6 days Details
NHBS Price: £66.99 $82/€75 approx

About this book

By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scientists, technicians, policy makers, security engineers, and law enforcement officials. Providing guidance to the broad international community, Laboratory Biosecurity Handbook addresses the objectives of biosecurity and the ways in which they overlap or conflict with those of biosafety.

The book describes the risks of working with dangerous pathogens and toxins in the current era of international terrorism. The authors characterize the global spread of legitimate biotechnology and relate it to the rise of transnational terrorism, emphasizing the need for biosecurity measures even in legitimate bioscience. The book discusses biosecurity risk assessment-a practical methodology that allows laboratory management and biosafety/biosecurity officers to analyze and determine the level of risk, and serves as a basis for managing those risks. The book includes questionnaires that can assist the process of collecting data for a biosecurity vulnerability assessment, example standard operating procedures and memoranda of understanding, and other useful reference material.

Addressing a variety of operating environments and the particular challenges they face when designing and implementing laboratory biosecurity, this book can assist bioscience facilities ranging from the large to the small, from those that focus on diagnosis or vaccine development, to those only minimally involved with infectious diseases. The detailed recommendations help avoid a "one-size-fits-all" approach to security and save limited resources. The book shows institutions how to develop and implement a biosecurity plan, and helps ensure that all components are included in the overall system, whether existing or new.


INTRODUCTION Laboratory Biosecurity and the Risks of Bioterrorism Laboratory Biosecurity and International Obligations Laboratory Biosecurity and National Regulations Approach/Objectives of this Book RISK ASSESSMENT Overview of Biosecurity Risk Assessment Methodology Characterize Assets and Threats Evaluate Scenarios Characterize the Risk Risk Reduction COMPONENTS OF BIOSECURITY Physical Security Personnel Security Material Control and Accountability Transport Security Information Security PROGRAM MANAGEMENT Role and Responsibilities Biosecurity System Design Response Force Performance Testing Documentation Assessments and Audits Training and Exercises SPECIFIC BIOSECURITY RECOMMENDATIONS Low-Risk Facility Moderate-Risk Facility High-Risk Facility Extreme Risk Facility Specific Biosecurity Recommendations - Low-Risk Facility Specific Biosecurity Recommendations - Moderate-Risk Facility Specific Biosecurity Recommendations - High-Risk Facility Specific Biosecurity Recommendations - Extreme High-Rick Facility CONCLUSIONS List of Acronyms Glossary Appendix A-Vulnerability Assessment Questionnaires Appendix B-Example Biosecurity Risk Assessment Methodology Appendix C-Biosecurity Plan Template Appendix D-Example Memorandum of Understanding with Local Law Enforcement Appendix E-SOP for Testing Access Control Systems Appendix F-Biosecurity Guidance and Regulations

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