Books  Animal & General Biology  Biochemistry & Molecular Biology 

Principles of Nucleic Acid Structures

By: S Neidle

Academic Press

Paperback | Nov 2007 | #171577 | ISBN-13: 9780123695079
Availability: Usually dispatched within 1 week Details
NHBS Price: £54.99 $69/€65 approx

About this book

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software.

Review of the previous edition"Stephen Neidle's excellent new introductory textbook will prove to be very timely, and provides a calm, balanced and objective study of the major advances."--Crystallography News


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