Books  Environmental Science  Toxicology 

A Practical Approach to Toxicological Investigations

By: Alan Poole and George B Leslie

Cambridge University Press

Paperback | Mar 2009 | #179841 | ISBN-13: 9780521105460
Availability: Usually dispatched within 6 days Details
NHBS Price: £27.99 $36/€33 approx

About this book

This book acknowledges that new drugs, food additives and other compounds need to be carefully screened for toxic side-effects. The bulk of this study is devoted to the practical questions of 'what toxicological studies should we perform?' and 'how should we perform them?'

Compounds which undergo toxicity testing may be conveniently categorised as those which are intended for administration to man and those which are not. The former include pharmaceuticals to be used medicinally or prophylactically and chemicals which are added to our food, drinks or medicine to improve their stability, appearance or palatability. Since it is on pharmaceuticals that the most comprehensive toxicological evaluations are generally performed, this book has been directed primarily towards to toxicological evaluation of potential new drugs. The principles and methodology of toxicological evaluation of other types of compounds are essentially similar. First published in 1989.


Contents

1. Introduction;
2. Regulatory requirements;
3. Animals: sources, selection, husbandry;
4. Standard studies in animals;
5. Measurements and observations made in living animals;
6. Terminal studies;
7. Specialised routes of exposure;
8. Reproductive toxicology;
9. Genotoxicity;
Appendices;
Index.

Write a review

There are currently no reviews for this product. Be the first to review this product!

Bestsellers in this subject

Human and Ecological Risk Assessment

NHBS Price: £95.50 $121/€112 approx

Fish Physiology, Volume 33

NHBS Price: £72.99 $93/€86 approx

Principles of Ecotoxicology

NHBS Price: £40.99 $52/€48 approx

Ecosystems and Human Health

NHBS Price: £98.99 $126/€116 approx

The Pesticide Manual

NHBS Price: £466.00 $592/€548 approx