Books  Animal & General Biology  Biochemistry & Molecular Biology 

MicroRNA Interference Technologies

By: Zhiguo Wang

205 pages, 23 b/w & col illus


Hardback | Jun 2009 | #182342 | ISBN-13: 9783642004889
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £149.00 $182/€167 approx

About this book

MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying species, with ever-increasing implications in the control of the fundamental biological processes and in the pathogenesis of adult humans.

This book provides comprehensive descriptions of the technologies and their applications to miRNA research and to new drug design for miRNA-related diseases. It starts with an overview of up-to-date knowledge of miRNA biology and the potential of miRNAs as therapeutic targets for human disease, followed by an introduction of the new concept of miRNA interference (miRNAi) and the perspectives of miRNAi technologies in general terms. In the following, each chapter introduces one of the miRNAi technologies with detailed descriptions of state-of-the-art design, procedures, principles and applications to basic research, R and D and clinical therapy.

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