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Histologic Basis of Mouse Endocrine System Development: A Comparative Analysis

By: Matthew Kaufman, Alexander Yu Nikitin and John P Sundberg

240 pages, 102 col illus

CRC Press

Hardback | Oct 2009 | #182684 | ISBN-13: 9781420088182
Availability: Usually dispatched within 6 days Details
NHBS Price: £95.00 $116/€107 approx

About this book

More than 3000 mutant mice strains have been created through genetic manipulation, and while many molecular techniques are straight forward, analysis of anatomic changes can be a challenge for even the best pathologist. To keep up with current interest in the endocrine system, this volume provides researchers with both a survey and a guide concerning use of the mutant mouse in histological studies of various glands.

Applying full color throughout, this atlas illustrates the similarities and differences between the mouse endocrine system and that of other species including humans. It includes approximately 50 high magnification color plates and a variety of sectioned embryos post conception.

!an excellent tool for the research lab and demonstrates the ability to enhance and utilize hematoxylin and eosin-stained (H&E) , sections of mouth embryogenesis from Dr. Kaufman's original research and improve through modern technology to further augment their usefulness. The ability of the reader to use his computer as a virtual microscope to enlarge, move, and investigate areas of interest on the specially digitized H&E slides of normal mouse embryogenesis on the accompanying DVD allow the researcher to analyze and compare endocrine development across species in addition to the well-labeled photomicrographs in the text itself and comparative dialogue. The advanced technology of enhancing key histological specimens lends excitement to this and other future textbooks. --Sandra L. Jex, DVM, in ALNMAG, April 2011, "Histologic Basis of Mouse Endocrine System Development nicely complements Kaufman's previous volumes on mouse development. It is an excellent reference for investigators specializing in the fields of embryology and endocrinology. It is also a useful reference for illustrating what is normal in tissues of variously aged mouse embryos. Therefore, it is useful for pathologists and other investigators wanting to evaluate histologic sections of mouse embryos for other purposes as well." --Journal of the American Association for Laboratory Animal Science, January 2011


Introduction. The Adrenal (Suprarenal) Gland. The Pituitary Gland. The Thyroid Gland. The Parathyroid Gland. The Pancreas. The Pineal Gland. Development of the Mammalian Gonads and Reproductive Ducts during the So-Called "Indifferent" Stage as Well as during the Fetal and Neonatal Period. The Ovary. The Testis.

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Matthew Kaufman, University of Edinburgh, Scotland Alexander Yu. Nikitin, Cornell University, Ithaca, New York, USA John P. Sundberg, The Jackson Laboratory, Bar Harbor, Maine, USA

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