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Understanding the Dynamics of Biological Systems: Lessons Learned from Integrative Systems Biology

Edited By: Werner Dubitzky, Jennifer Southgate and Hendrik Fuss


Hardback | Jan 2011 | #189959 | ISBN-13: 9781441979636
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £149.00 $191/€178 approx

About this book

The book encompasses the key disciplines of biology, mathematics, and information technology that contribute to systems biology. It introduces some of the main methods and techniques of systems biology and assesses their contributions based on case studies. The biological phenomena investigated include tissue organization, hormonal control, bacterial stress response, tumor growth and cellular metabolism. Each chapter serves simultaneously as design blueprint, user guide, research agenda and communication platform.


Preface.- Effects of Protein Quality Control Machinery on Protein Homeostasis.- Metabolic Network Dynamics: Properties and Principles.- A Deterministic, Mathematical Model for Hormonal Control of the Menstrual Cycle.- Modelling Transport Processes and their Implications for Chemical Disposition and Action.- Systems Biology of Tuberculosis: Insights for Drug Discovery.- Qualitative Analysis of Genetic Regulatory Networks in Bacteria.- Modelling Antibiotic Resistance in Bacterial Colonies Using Agent-Based Approach.- Modelling the Spatial Pattern Forming Modules in Mitotic Spindle Assembly.- Cell-Centred Modelling of Tissue Behaviour.- Interaction-Based Simulations for Integrative Spatial Systems Biology.- Glossary.- Index.

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