Books  Animal & General Biology  Biochemistry & Molecular Biology 

Nuclear Organization and Function

By: Terri Grodzicker, David Spector, David Stewart and Bruce Stillman

650 pages, illus

Cold Spring Harbor Laboratory Press

Paperback | Jun 2011 | #191658 | ISBN-13: 9781936113088
Availability: Usually dispatched within 6 days Details
NHBS Price: £108.00 $136/€128 approx
Hardback | Jun 2011 | #191659 | ISBN-13: 9781936113071
Availability: Usually dispatched within 6 days Details
NHBS Price: £267.00 $337/€316 approx

About this book

This volume is based on presentations by the world-renowned investigators who gathered at the 75th annual Cold Spring Harbor Symposium on Quantitative Biology to discuss the organization and function of the cell nucleus. It reviews the latest advances in research into nuclear structure, the organization of the genome within the nucleus, and spatiotemporal coordination of nuclear processes. The topics examined include nuclear domains, chromatin organization, transcription and RNA processing, DNA replication, nuclear reprogramming, and epigenetics. Cancer, premature aging syndromes, and other diseases that may be associated with altered nuclear organization are also covered.

The hardback edition of this book features additional online access.


Contents

INTRODUCTION

CHROMATIN MODIFICATIONS AND GENE EXPRESSION

DNA REPLICATION AND GENOME INTEGRITY

REPROGRAMMING AND DIFFERENTIATION

RNA BIOLOGY

CHROMOSOME STRUCTURE AND MITOSIS

HETEROCHROMATIN FORMATION AND GENE SILENCING

TRANSCRIPTION MEETS RNA PROCESSING

NUCLEAR PERIPHERY

CHROMATIN STRUCTURE AND ORGANIZATION

GENOME REGULATION

SUMMARY

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