Books  Animal & General Biology  Biochemistry & Molecular Biology 

The Biology of Lipids: Trafficking, Regulation, and Function

Edited By: Kai Simons

334 pages, 45 colour and 33 b/w illustrations

Cold Spring Harbor Laboratory Press

Hardback | Aug 2011 | #192621 | ISBN-13: 9781936113392
Availability: Usually dispatched within 6 days Details
NHBS Price: £106.00 $134/€126 approx

About this book

As the major structural component of cell membranes, lipids not only serve as barriers but also play active roles in cellular function. In this volume, contributors explore the synthesis, metabolism, and distribution of lipid species in the cell; the composition of lipid rafts and their roles in protein trafficking and signaling; and the biophysical behavior of lipids and membranes.


Contents

Contents

- Membrane Organization and Lipid Rafts
Kai Simons and Julio L. Sampaio
- Shotgun Lipidomics on High Resolution Mass Spectrometers
Dominik Schwudke, Kai Schuhmann, Ronny Herzog, Stefan R. Bornstein, and Andrej Shevchenko
- Model Answers to Lipid Membrane Questions
Ole G. Mouritsen
- Phase Separation in Lipid Membranes
Frederick A. Heberle and Gerald W. Feigenson
- Lipid Polymorphisms and Membrane Shape
Vadim A. Frolov, Anna V. Shnyrova, and Joshua Zimmerberg
- Curvature-Driven Lipid Sorting in Biomembranes
Andrew Callan-Jones, Benoit Sorre, and Patricia Bassereau
- Lipid Simulations: A Perspective on Lipids in Action
Ilpo Vattulainen and Tomasz Rog
- Fluorescence Techniques to Study Lipid Dynamics
Erdinc Sezgin and Petra Schwille
- Dynamic Transbilayer Lipid Asymmetry
Gerrit van Meer
- Glycosphingolipid Functions
Clifford A. Lingwood
- Regulation of Cholesterol and Fatty Acid Synthesis
Jin Ye and Russell A. DeBose-Boyd
- Distribution and Functions of Sterols and Sphingolipids
J. Thomas Hannich, Kyohei Umebayashi, and Howard Riezman
- Phosphoinositides in Cell Architecture
Annette Shewan, Dennis J. Eastburn, and Keith Mostov
- Specificity of Intramembrane Protein-Lipid Interactions
Francesc-Xabier Contreras, Andreas Max Ernst, Felix Wieland, and Britta Br#gger
- Synthesis and Biosynthetic Trafficking of Membrane Lipids
Tomas Blom, Pentti Somerharju, and Elina Ikonen
- Lipid-Mediated Endocytosis
Helge Ewers and Ari Helenius
- Not Just Fat: The Structure and Function of the Lipid Droplet
Toyoshi Fujimoto and Robert G. Parton
- Lysosomal Lipid Storage Diseases
Heike Schulze and Konrad Sandhoff
- Role of Lipids in Virus Replication
Maier Lorizate and Hans-Georg Kr#usslich

Index

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