Books  Animal & General Biology  Genetics 

Forward-Time Population Genetics Simulations: Methods, Implementation, and Applications

By: Bo Peng, Marek Kimmel and Christopher L Amos

234 pages, b/w illustrations, tables

Wiley-Blackwell

Paperback | Mar 2012 | #194865 | ISBN-13: 9780470503485
Availability: Usually dispatched within 5 days Details
NHBS Price: £65.50 $84/€78 approx

About this book

The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful.


Contents

Preface ix
Acknowledgments xiii
List of examples xxiii

1. Basic concepts and models 1
2. Simulation of population genetics models 25
3. Ascertainment bias in population genetics 47
4. Observing properties of evolving populations 63
5. Simulating populations with complex human diseases 89
6. Nonrandom mating and its applications 125

Appendix: Forward-time simulations using stimulPOP 157


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