Books  Animal & General Biology  Biochemistry & Molecular Biology 

Systems Chemical Biology: Integrating Chemistry and Biology Through Cheminformatics Approaches

By: Andreas Bender (Author), Rajarshi Guha (Author), Josef Scheiber (Author)

John Wiley & Sons

Hardback | May 2018 | #199146 | ISBN-13: 9780470554470
Available for pre-order: Due May 2018 Details
NHBS Price: £66.95 $82/€75 approx

About this book

This book will provide a descriptive outline of both the fundamental and the applied aspects of systems chemical biology approaches, focused primarily on the drug discovery context. It will cover a broad range of aspects related to prediction of phenotypic outcome to interfering with key pathways, as well as the design of small molecule modulators aimed at causing a desired phenotype (or to reverse a given diseased phenotype). These relate to both cellular pathways with the goals of understanding and predicting function, and to strategies in multi-drug targeting. This can also be gauged from the rapid growth in the literature in this direction and the creation of new computational/bioinformatics journals.

The book will also provide an overview, with easy-to-understand chapters written by pioneers and leaders in the field, as well as advanced material, to inform the readers of the potential caveats which might be involved in a particular task at hand.  It also clearly highlight the scope of Systems Chemical Biology and includes case studies where computational network models have provided experimental insight.

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