380 pages, colour & b/w photos, colour & b/w illustrations, tables
Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation.
Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics – what genes are, what they do, and how they do it – as well as how genes behave in populations and how evolution influences them. The following section provides an overview of the different kinds of genetic variation in humans, and how this variation is analyzed and used to make evolutionary inferences. The third section concludes with a presentation of the current state of genetic evidence for human origins, the spread of humans around the world, the role of selection and adaptation in human evolution, and the impact of culture on human genetic variation. A final, concluding chapter discusses various aspects of molecular anthropology in the genomics era, including personal ancestry testing and personal genomics.
An Introduction to Molecular Anthropology is an invaluable resource for students studying human evolution, biological anthropology, or molecular anthropology, as well as a reference for anthropologists and anyone else interested in the genetic history of humans.
Chapter 1 Genes: How they are inherited 1
Chapter 2 What genes are, what they do, and how they do it 15
Chapter 3 Genes in populations 27
Chapter 4 A simple model: Hardy–Weinberg equilibrium 35
Chapter 5 Evolutionary forces 45
Chapter 6 Molecular evolution 69
Chapter 7 Genetic markers 79
Chapter 8 Sampling populations and individuals 103
Chapter 9 Sampling DNA regions 111
Chapter 10 Analysis of genetic data from populations 125
Chapter 11 Analysis of genetic data from individuals 147
Chapter 12 Inferences about demographic history 175
Chapter 13 Our closest living relatives 201
Chapter 14 The origins of our species 211
Chapter 15 Ancient DNA 229
Chapter 16 Dispersal and migration 247
Chapter 17 Species-wide selection 283
Chapter 18 Local selection 299
Chapter 19 Genes and culture 321
Chapter 20 Ongoing and future developments in molecular anthropology 341
Suggestions for additional reading 373
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