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Introduction to Bioinformatics

Aimed primarily at a biological audience, it is ideal for those without detailed prior knowledge of programming who are encountering bioinformatics for the first time
Frequent examples, self-test questions, problems, and exercises are incorporated throughout the text to encourage self-directed learning
Emphasises the practical applications of the subject to a wide range of disciplines, such as molecular biology, medicine, forensic science and anthropology
Invaluable information retrieval techniques and data calculations are covered to enable the reader to carry out their own research on the Web
The Online Resource Centre includes data sets and Web-based problems, alongside guidance for answering the problems and exercises in the book.

By: Arthur M Lesk (Author)

379 pages, 8 plates with colour illustrations; b/w illustrations, tables

Oxford University Press

Paperback | Nov 2013 | Edition: 4 | #206873 | ISBN-13: 9780199651566
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NHBS Price: £32.99 $40/€37 approx

About this book

A vast amount of biological information about a wide range of species has become available in recent years as technological advances have significantly reduced the time it takes to sequence a genome or determine a novel protein structure. This text describes how bioinformatics can be used as a powerful set of tools for retrieving and analysing this biological data, and how bioinformatics can be applied to a wide range of disciplines such as molecular biology, medicine, biotechnology, forensic science and anthropology.

Fully revised and updated, the fourth edition of Introduction to Bioinformatics contains two new chapters, with significantly increased coverage of metabolic pathways, and gene expression and regulation. This reflects the recent growth of interest in these areas in the field of bioinformatics. Written primarily for a biological audience without a detailed prior knowledge of programming, Introduction to Bioinformatics is the perfect introduction to the field of bioinformatics, providing friendly guidance and advice on how to use various methods and techniques. Furthermore, frequent examples, self-test questions, problems, and exercises are incorporated throughout the text to encourage self-directed learning.

New to this edition:
- The 'Weblems' (Web-based problems) are now online to enable immediate access to hyperlinked materials and are tied more closely to specific areas of the text.
- Two new chapters have been written to increase the coverage of metabolic pathways and gene expression and regulation, in order to reflect the recent growth of interest in these areas.
- Extended coverage of genomics reflects the increasing cross-over between the disciplines of bioinformatics and genomics.
- Increased emphasis is placed on the exciting potential of bioinformatics to enable future advances in our understanding of life on earth.

Reviews from previous editions:

"An essential textbook for undergraduate students who are interested in a comprehensive introduction to the multidisciplinary field of bioinformatics."
– Jean-Christophe Nebel, Kingston University

"I'm impressed with the breadth AND depth achieved in what is a reasonably compact text. There are lots of quite innovative features which support the pedagogical delivery of the material."
– Richard Badge, University of Leicester

"A very good introductory textbook in bioinformatics. It is well-structured and nicely laid out. There are numerous examples and problems attached to each chapter, including the novel Weblems."
– Karen Page, University College London

Related titles

See the previous edition

Introduction to Bioinformatics

Life in a post-genomic age has the promise to revolutionize our...

NHBS Price: £28.99 $35/€33 approx


Chapter 1 Introduction
Chapter 2 Genome organization and evolution
Chapter 3 Scientific publications and archives: media, content and access
Chapter 4 Archives and information retrieval
Chapter 5 Alignments and phylogenetic trees
Chapter 6 Structural bioinformatics and drug discovery
Chapter 7 Introduction to systems biology
Chapter 8 Metabolic pathways
Chapter 9 Gene expression and regulation

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Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University, USA.

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