Books  Animal & General Biology  Biochemistry & Molecular Biology 

Integins: Molecular and Biological Responses to the Extracellular Matrix

Series: Biology of Extracellular Matrix Series

By: DA Cheresh and RP Mecham

Academic Press

Hardback | Nov 1994 | #37467 | ISBN: 0121711609
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £155.00 $197/€185 approx

About this book

Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered in "Receptors for Extracellular Matrix". It addresses some of the most exciting areas of integrin biology, including the varied roles of integrins in cell division, differentiation, movement, wound healing, inflammation, thrombosis, osteoporosis, and cancer. Among its key features, it: describes key aspects of integrin structure, function, and biology; covers collagen receptors, epithelial cell integrins, leukocyte integrins, platelet integrins, integrin signaling, and integrin antagonists; investigates the expression and role of integrins during development and in the cytoskeleton; and includes the actions and influences of integrins in inflammation, thrombosis, and osteoporosis.


Contents

J.W. SMITH, The Structural Basis of Integrin-Ligand (RGD) Interaction. M.A. SCHWARTZ, Integrins as Signal Transducing Receptors. K.O. SIMON and K. BURRIDGE, Interactions Between Integrins and the Cytoskeleton: Structure and Regulation. J ASHKENAS, C.H. DAMSKY, M.J. BISSELL, And Z.WERB, Integrins, Signaling, And the Remodeling of the Extracellular Matrix. T. LALLIER, M.D. HENS, And D.W. DESIMONE, Integrins in Development. V QUARANTA, R.N. TAMURA, G. COLLO, H.M. COOPER, M. HORMIA, C. ROZZO, G. GAIETTA, And L. STARR, Distinctive Functions of Alpha6beta4 and Other Interactions in Epithelial Cells. M.J. ELICES, Leukocyte Integrins. T.J. KUNICKI and Z.R. RUGGERI, Molecular Properties of Human Platelet Integrin Alphaiibbeta3. J.M. STADEL, A.J. NICHOLS, D.R. BERTOLINI, And J.M. SAMANEN, Therapeutic Potential of Integrin Antagonists. Subject Index.

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