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Applications of Proteomics to Cell Signaling

Handbook / ManualCancelled
Describes proteomic methods chapters and their applications to specific areas of cell signaling
Presents mass spectrometry and associated computational techniques to identify protein alterations during signal transduction
Discusses protein post-translational modification-specific proteomic methods
Covers proteomics of fungal species involved in alternative energy production

Series: Methods in Signal Transduction Series

By: Iyer Srinivas (Author)

352 pages, b/w illustrations

CRC Press

Hardback | May 2015 | #220586 | ISBN-13: 9781439840108
Publication cancelled Details

About this book

The field of proteomics has had a tremendous impact on our understanding of biological systems. While proteomics encompasses multiple approaches, the application of mass spectrometry-based techniques has generated large, information-rich data sets that have enabled a much clearer understanding of areas such as cell signaling. For example, protein post-translational modifications such as phosphorylation are critically involved in signal transduction in almost all biological systems; much progress has been made to identify these protein alterations during signal transduction. Applications of Proteomics to Cell Signaling focuses specifically on the application of these approaches to understanding signaling in biological systems.


Protein Identification Methodology, Shixin Sun
Database Searching and Software Tools, Sanjeev Bhardwaj
Separations: nano HPLC, Katianna Pihakari
Stable Isotope Assisted Quantitation, Akhilesh Panday
AQUA Peptides and Quantitative Post-Translational Modification Measurement, Steven Gygi

Signaling in Bacterial Communication and Metabolism: Quorum Sensing and Antibiotic Detoxifixation Pathways, David Fox and Andy Koppisch
Fungal Signaling in Cellulose Degradation, Taraka Dale and Paul Langan
Phosphorylation in Cancer Signaling: Emphasis on Computational Approaches to Process Proteomic Data Sets, Bill Hlavacek
Glycosylation in Cell Surface Receptor Recognition Events, Sheng Gu
Pathways Involvedi Toxicological Responses to Particulate Matter, Jun Gao, Rashi Iyer, and Andrij Holiau

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Iyer Srinivas is a Staff Scientist at Los Alamos National Laboratory in New Mexico.

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