Practical Issues in Performing Comparative Molecular Studies: Y. Suh, J.A. Blake, and M.J. Braun, Equipping and Organizing Comparative Laboratory Molecular Genetics. K.J. Sytsma, T.J. Givnish, J.F. Smith, and W.J. Hahn, Collection and Storage of Land Plant Samples for Macromolecular Comparisons. R.L. Cann, R.A. Feldman, L.A. Freed, J.K. Lum, and C.A. Reeb, Collection and Storage of Vertebrate Samples. M. Dick, D.M. Bridge, W.C. Wheeler, and R. DeSalle, Collection and Storage of Invertebrate Samples. M. Blackwell and R.L. Chapman, Collection and Storage of Fungal and Algal Samples. Comparing Macromolecules: Exploring Biological Diversity: Comparisons at Protein Level: C.J.Bult and Y.-T. Kiang, One-Dimensional Electrophoretic Comparisons of Plant Proteins. J. Britton-Davidian, Starch Gel Electrophoresis in Vertebrates. D. Goldman and S.J. O'Brien, Two-Dimensional Protein Electrophoresis in Phylogenetic Studies. N. Tuross and L. Stathoplos, Ancient Proteins in Fossil Bones. M.H.V. Van Regenmortel, C. Joisson, and C. Wetter, Comparative Immunological Methods. E.M. Prager and A.C. Wilson, Information Content of Immunological Distances. Comparisons at Nucleic Acid Level: D.B. Stein, Isolation and Comparison of Nucleic Acids from Land Plants: Nuclear and Organellar Genes. J.M. Chesnick and R. Cattolico, Isolation of DNA from Eukaryotic Algae. R. DeSalle, A.K. Williams, and M. George, Isolation and Characterization of Animal Mitochondrial DNA. A.L. Rayburn, Comparative Studies of Genome Content. M.A. Batzer, C.W. Schmid, and P.L. Deininger, Evolutionary Analyses of Repetitive DNA Sequences. M.S. Springer and R.J. Britten, DNA-DNA Hybridization of Single-Copy DNA Sequences. S.O. Rogers, G.C. Beaulieu, and A.J. Bendich, Comparative Studies of Gene Copy Numbers. J.L. Slightom, Optimal Preparative Methods for Producing Comparative Gene Libraries. S.H. Rogstad, Surveying Plant Genomes for Variable Number of Tandem Repeat Loci. B.M. Bowditch, D.G. Albright, J. Williams, and M.J. Braun, Use of Randomly Amplified Polymorphic DNA Markers in Comparative Genome Studies. S.L. Martin and H.A. Wichman, Molecular Approaches to Mammalian Retrotransposon Isolation. I. Felger and J.A. Hunt, Detection and Characterization of Transposable Elements. C.P. Kurtzman, DNA-DNA Hybridization Approaches to Species Identification in Small Genome Organisms. J.-P. Bachellerie and L.-H. Qu, Direct Ribosomal-RNA Sequencing for Phylogenetic Studies. J.F. Senecoff and R.B. Meagher, In Vivo Analysis of Plant 18S Ribosomal-RNA Structure. D. Stahl, Comparison of Nucleic Acids from Microorganisms: Sequencing Approaches. W.K. Thomas and T.D. Kocher, Sequencing of Polymerase Chain Reaction-Amplified DNAs. B.H. Bowman and S.R. Palumbi, Rapid Production of Single-Stranded Sequencing Template from Amplified DNA Using Magnetic Beads. W.K. Thomas and S. Paabo, DNA Sequences from Old Tissue Remains. E.P. Lessa, Analysis of DNA Sequence Variation at Population Level by Polymerase Chain Reaction and Denaturing Gradient Gel Electrophoresis. S.-Y. Chang, A. Shih, and S. Kwok, Detection of Variability in Natural Populations of Viruses by Polymerase Chain Reaction. K.E. Holsinger and R.K. Jansen, Phylogenetic Analysis of Restriction Site Data. D.M. Hillis, M.W. Allard, and M.M. Miyamoto, Analysis of DNA Sequence Data: Phylogenetic Inference. Comparing Macromolecules: Exploring Evolutionary Pattern and Process: B. Reinhold-Hurek and D.A. Shub, Experimental Approaches for Detecting Self-Splicing Group I Introns. L.N.W. Kam-Morgan, T.B. Lavoie, S.J. Smith-Gill, and J.F. Kirsch, Site-Directed Mutagensis in Analysis of Protein-Protein Interactions. P.K. Tucker and B. Lundrigan, Comparative Studies of Mammalian Y Chromosome. G.A. Dover, A.R. Linares, and J.M. Hancock, Detectionand Quantification of Concerted Evolution and Molecular Drive. E.R. Jupe and E.A. Zimmer, Assaying Differential Ribosomal RNA Gene Expression with Allele-Specific Probes. D.M. Irwin, Assays for Copy Number, Differential Expression, and Recombination in Lysozyme Multigene Family. G. Wistow, Identification of Lens Crystallins: A Model System for Gene Recruitment. P. Shih, B.A. Malcolm, S. Rosenberg, J.F. Kirsch, and A.C. Wilson, Reconstruction and Testing of Ancestral Proteins. C.-B. Stewart, Comparative Method in Study of Protein Structure and Function: Enzyme Specificity as an Example. B.G. Hall and B. Hauer, Acquisition of New Metabolic Activities by Microbial Populations. D.E. Dykhuizen, Chemostats Used for Studying Natural Selection and Adaptive Evolution. S. Jinks-Robertson and T.D. Petes, Experimental Determination of Rates of Concerted Evolution. A.D. Ellington, Experimental Testing of Theories of an Early RNA World. Author Index. Subject Index.