Reviews the basic biology of sex determination and summarises ground-breaking work in mouse, marsupial and Drosophila systems. Also covers current human genetics, clinical studies and the syndromes of abnormal sex differentiation.
Many of the individual contributions to this book are excellent stand-alone reviews, and the book as a whole constitutes a valuable source of information on sex determination, the X and Y chromosomes, and sexual development-bothnormal and abnormal-in humans and mice. I found the rather personal chapter by Hampikian et al. on marsupials to be particularly useful in conjunction with the Drosophila chapter; together they provide a sense of the commonalities and differences that determine sexual dimorphism in each of these groups relative to each other and to the eutherian mouse-human group. --SCIENCE "This book contains all you ever wanted to know about mammalian sex determination but were afraid to ask!... In all honesty, this is really a very good book which will provide an invaluable source of reference." --HEREDITY
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