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Contents
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About this book
Reviews the basic biology of sex determination and summarises ground-breaking work in mouse, marsupial and Drosophila systems. Also covers current human genetics, clinical studies and the syndromes of abnormal sex differentiation.
Contents
Part I: S.S. Wachtel and T.R. Tiersch, The Search for the Male Determining Gene. A. Sinclair, The Cloning of SRY. J. Gubbay and R. Lovell-Badge, The Mouse Y Chromosome. A. McLaren, XX Sex Reversal in the Mouse. C.M. Nagamine, XY Sex Reversal in the Mouse. S. Ohno, Conservation of the X-Linkage Group in Toto by all Eutherian Mammals. M.F. Lyon, X-Chromosome Inactivation. G.K. Hampikian, D.W. Cooper, J.A. Marshall Graves, Sex Determination in Marsupials and Monotremes. C. Cronmiller and H.K. Salz, The Feminine Mystique: The Initiation of Sex Determination in Drosophila. Part II: U. Muller, The Human Y Chromosome. N.A. Affara and M.A. Ferguson-Smith, DNA Sequence Homology between the Human Sex Chromosomes. S.S. Wachtel, XX Sex Reversal in the Human. S.S. Wachtel and J.L. Simpson, XY Sex Reversal in the Human. K.Neeley and R.G. Rosenfeld, Phenotypic Correlations of X Chromosome Loss. L. Pinsky, M. Trifiro, L.K. Beitel, and M. Kaufman, Molecular Genetics of Androgen Insensitivity Syndromes in Man. M. Zachmann, Male Pseudohermaphroditism. M.I. New and C. Crawford, Molecular Genetics of Steroid 21-Hydroxylase Deficiency. N. Josso, S. Imbeaud, J.-Y. Picard, and R.L. Cate, The Gene for Anti-Mullerian Hormone. M.L. Gustafson and P.K. Donahoe, Mullerian Inhibiting Substance: Critical Roles in Sexual Differentiation.
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