Books  Animal & General Biology  Genetics 

Transgenic Animals

Out of Print

Edited By: F Grosveld

Academic Press

Hardback | Dec 1992 | #34708 | ISBN: 0123045304
Out of Print Details

About this book

Although the technology required to produce transgenic animals is well established, their potential is far from being fully realized. In this book, discussion of the structural and biological background of the generation of transgenic animals provides the setting for experts throughout the biological sciences to describe what advances have been made in their disciplines using transgenic animals and what can be achieved in the future. Transgenic Animals is an invaluable guide for all molecular biologists, immunologists, neurobiologists, developmental biologists and those involved in clinical research, who have considered using this powerful technique but remain unsure of its possibilities.


Contents

The regulatory domain organization of eukaryotic genomes - implications for stable gene transfer, A.E. Sipple, et al; stable gene transfer directed modification of genes by homologous recombination in mammalian cells, S. Doi, et al; transgenic strategies in mouse embryology and development, R.S.P. Beddington; study of gene regulation in transgenic mice, G. Kollias and F. Grosveld; genome imprinting, W. Reik; engineering cellular defects in transgenic mice by genetic ablation, M.L. Breitman and A. Bernstein; transgenic mice in immunology, A.L. Mellor; transgenic mice in neurobiology, W.D. Richardson; oncology and transgenic mice, D. Kioussis; retrovirus vectors for gene therapy procedures, D. Valerio; germline manipulation - applications in agriculture and biotechnology, A.J. Clark, et al.

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