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Vibrio Cholerae and Cholera: Molecular to Global Perspectives

Out of Print

Edited By: I Wachsmuth

400 pages, Illus

American Society for Microbiology

Hardback | Dec 1994 | #39693 | ISBN: 1555810675
Out of Print Details

About this book

THE RETURN OF AN ANCIENT DISEASE With the re-emergence and rapid spread of cholera in Latin America after an absence of 100 years, there is a renewed interest and concern about this ancient disease. This new book addresses the arrival of the 7th pandemic in the Western Hemisphere and its increased importance in Africa and Asia during the past two years. The research also contrasts the pandemic with low-level endemic


Introduction; The bacterium Vibrio cholerae,; Isolation and identification of toxigenic Vibrio cholerae 01 from fecal specimens; Toxigenic Vibrio cholerae in food and water; Detection of cholera toxin genes; Detection of toxins of Vibrio cholerae 01 and non-01; Non-toxigenic Vibrio cholerae 01 infections in the United States; Molecular basis for O-antigen biosynthesis in Vibrio cholerae 01; Ogawa-Inaba switching; Non-O group 1 Vibrio cholerae; Vibrios in the environment; Serologic diagnosis of Vibrio cholerae 01 infection; Virulence factors; Toxins of Vibrio cholerae 01; Regulation of toxin (CT) expressions; The toxin-coregulated pilus: biogenesis and function; Animal models in cholera research; Cholera: the disease; Cholera: pathophysiology; Immunity to Vibrio cholerae infection; Host susceptibility; Epidemiology and surveillance; Cholera before 1970; The African epidemic 1970-92; Endemic cholera in Australia and the United States; The Latin American epidemic; Transmission of cholera; Molecular epidemiology of Vibrio cholerae 01; Cholera surveillance; Vaccines; Polysaccharide-protein conjugate vaccines for prevention of cholera; Molecular recombinant cholera vaccines; Protective oral cholera vaccine based on a combination of cholera toxin B subunit and inactivated Cholera vibrios; Public health consideration for the use of cholera vaccines in cholera control programs; Cholera: the future; Cholera: unanswered questions

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