Biology of the Germ Line In Man and Animals

About this book

This volume highlights valuable new knowledge and technological progress resulting from a special 4-year research project in Japan on the molecular mechanisms underlying the maintenance of germ lines in animals and man. The 19 selected topics focus on the molecular mechanisms of gamete differentiation, fertilization, nidation and placentation, and blastomere differentiation in early mammalian development. Taken together, they provide readers with an overview of the state of the art of reproductive biology in Japan.

Contents

Control of M-phase by MPF/cyclin-dependent cdc2 kinase, T. Kishimoto; molecular biology of human Y chromosome, Y. Nakagome et al; PCR evaluation of separation of X- and Y-bearing sperm, H. Mohri et al; mechanism of spermatogenesis in amphibians - in vitro study, S. Abe; roles of c-kit receptor and its ligand for germ cell differentiation, Y. Kitamura et al; paracrine/autocrine regulation in the murine reproductive processes, M. Takahashi et al; regulatory mechanisms of sperm motility, M. Morisawa; involvement of protein kinase C in sperm-egg interaction, S. Suzuki et al; role of cumulus oophorus in mammalian fertilization, Y. Toyoda et al; signal transduction of gamete interaction and intracellular calcium release mechanism at fertilization of mammalian eggs, S. Miyazaki et al; remodeling of sperm nuclear basic proteins during spermatogenesis and fertilization in Anuran amphibians, C. Katagiri et al; molecular understanding of fertilization and development, M. Hatanaka; attenuation of mammalian in vitro developmental block through protection from oxygen toxicity, Y. Noda et al; factors affecting the development of intact and nuclear transplanted embryos, A. Iritani; autonomy and heteronomy in embryogenesis of muridate rodents, C. Tachi; search for new cell-surface recognition molecules important in mammalian embryogenesis, T. Muramatsu; immunological studies on mammalian fertilization and implantation, T. Mori; co-operative roles of oocyte and follicle in ovarian parthenogenesis and teratocarcinogenesis in mice - evidence from chimeric mice, M. Noguchi et al; introduction of foreign genes into germ line cells of animals - production of viral disease models, Y. Iwakura.

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