Molecular Biology of the Gene, Volume 1

Contents

VOLUME I General Principles.I: HISTORICAL BACKGROUND. 1. The Mendelian view of the World. 2. Cells Obey the Laws of Chemistry. 3. Nucleic Acids Convey Genetic Information. II: CHEMICAL FACTS AND PRINCIPLES. 4. A Chemist's Look at the Bacterial Cell. 5. The Importance of Weak Chemical Interactions. 6. Coupled Reactions and Group Transfers. III: BACTERIAL GENETICS. 7. The Genetic Systems Provided by E. coli and Its Viruses. 8. The Fine Structure of Bacterial and Phase Genes. IV: DNA IN DETAIL. 9. The Structures of DNA. 10. The Replication of DNA. 11. Recombination at the Molecular Level. 12. The Mutability and Repair of DNA. V: THE STEPS IN PROTEIN SYNTHESIS. 13. The Synthesis of RNA upon DNA Templates. 14. Involvement of RNA in Protein Synthesis. 15. The Genetic Code. VI: REGULATION OF GENE FUNCTION IN BACTERIAL CELLS. 16. Regulation of Protein Synthesis and Function in Bacteria. 17. The Replication of Bacterial Viruses. VII: FACING UP TO EUKARYOTIC CELLS. 18. Yeasts as the E. coli of Eukaryotic Cells. 19. Recombinant DNA at Work. VIII: THE FUNCTIONING OF EUKARYOTIC CHROMOSOME. 20. The Unexpected Structures of Eukaryotic Genomes. 21. The Functioning of Higher Eukaryotic Genes. VOLUME II Specialized Aspects.IX: GENE FUNCTION IN SPECIALIZED EUKARYOTIC SYSTEMS. 22. The Molecular Biology of Development. 23. The Generation of Immunological Specificity. 24. The Extraordinary Diversity of Eukaryotic viruses. X: CANCER AT THE GENETIC LEVEL. 25. The Control of Cell Proliferation. 26. The Genetic Basis of Cancer. 27. The Origins of Human Cancer. XI: EVOLUTION OF THE GENE. 28. The Origins of Life.

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