Bioenergetics at a Glance

About this book

An introduction and guide to one of the key areas of biochemistry.

Contents

Scope of bioenergetics The 'universal' view of energy The 'local' view of energy Equilibrium and equilibrium constants Sources of biological energy - quantitation Direct coupling of oxidation to anhydride formation Oxygen as an oxidising agent Respiratory carriers Respiratory chain (mitochondrial) Respiratory assemblages (mitochondrial) Mechanism of electron flow between proteins Variations within respiratory chains Light trapping and water splitting in chloroplasts Reaction centre structure Organisation of membrane proteins (chloroplast) Photosynthetic bacteria Concepts of energy transduction- redox-anhydride bond energy Transfer via H+gradient - I. Qualitative aspects II. Kinetic aspects Quantitative aspects - I. H+/O ratio II. DGp/DMH+ How does electron transfer generate H+ (I) + (II) ATP synthase complex F1 structure F0 structure Coupling H+ gradient to ATP synthesis - energetics structural aspects Integration with cytoplasm - mitochondria Aspects of control - qualitative:quantitative Integration of cytoplasm/control - chloroplasts Uncouplers and ionophores in studies of phosphorylation Mitochondrial defects Alternative uses of H+ gradient Alternative gradient production ATP driven ion pumps - a broader perspective E-P pumps Evolution of pumps Evolution of organelles

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