Books  Animal & General Biology  Biochemistry & Molecular Biology 

Strategies in Transgenic Animal Science

Out of Print

Edited By: GM Monastersky and M Robl

375 pages, 50 illus

American Society for Microbiology Press

Hardback | Dec 1995 | #48973 | ISBN: 1555810969
Out of Print Details

About this book

Focuses on how transgenic animals are used to investigate fundamental questions in biomedical and biotechnological research.


Contents

Part I: General Transgenic Strategies; Transgenic mouse strategies: embryology and animal science; Preimplantation rat embryology: chimeric and transgenic strategies; Nonrodent transgenic strategies; Embryonic stem cell strategies: beyond the mouse model; Part II: Transgenic Strategies in Biomedical Research; Transgenic strategy for studying viral pathogenesis; Strategies for studying cardiovascular diseases in transgenic and gene-targeted mice; Strategies in the development of transgenic animal models for fl-amyloid-related neuropathologies of Alzheimer's disease; Transgenic strategies used to study diabetes and obesity; Transgenic strategies for satudying cholesterol metabolism; Transgenic strategies for studying autoimmunity; Mouse models of human genetic diseases and the develeopment of human gene therapy protocols; Transgenic strategies for studying poliovirus pathogenesis and immunology; Part III: Specialized Applications of Transgenics in Research; Transgenic strategies in toxicology; Trans-immortalization strategies in transgenics; The H-2K tsA58 transgenic mouse as a single source of a wide range of conditionally immortal cell lines; Index

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