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Foundations of Cellular Neurophysiology


By: D Johnston and S Miao-Sin Wu

676 pages, Figs

MIT Press

Hardback | Dec 1994 | #54552 | ISBN: 0262100533
Availability: Usually dispatched within 5 days Details
NHBS Price: £72.95 $89/€82 approx

About this book

Problem solving is an indispensable part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience contains comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It provides detailed derivations of equations, worked examples, and homework problem sets (with complete answers). Developed from notes for the course that the authors have taught since 1983 at Baylor College of Medicine, USA, this text covers cellular neurophysiology (also some material at the molecular and systems levels) from its physical and mathematical foundations.


Ion movement in excitable cells; electrical properties of the excitable membrane; functional properties of dendrites; nonlinear properties of excitable membranes; Hodgkin and Huxley's analysis of the squid giant axon; functional diversity of voltage-gated ionic conductances; molecular structure and unitary currents of ion channels; stochastic analysis of single-channel function; formulation of stochastic channel mechanisms; synaptic transmission I - presynaptic mechanisms; synaptic transmission II - Ca2+ and transmitter release; synaptic transmission III - postsynaptic mechanisms; extracellular field recordings; cellular neurophysiology of learning and memory. Appendices: basic electricity and electrical circuits; optical methods in cellular neurophysiology; short answers to homework problems; complete solutions to problems.

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