Books  Animal & General Biology  Biochemistry & Molecular Biology 

Receptors: Models for Binding, Trafficking, and Signaling

By: DA Lauffenburger and J Linderman

384 pages, 75 line illus

Oxford University Press USA

Paperback | May 1996 | #56016 | ISBN: 0195106636
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £105.00 $132/€125 approx

About this book

Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes-from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.


"Bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modelling approach combines with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. . . . conceptually rich, timely, and useful." --Biology Digest


Contents

Introduction; 1. Cell Surface Receptor/Ligand Binding Fundamentals; 2. Receptor/Ligand Trafficking; 3. Physical Aspects of Receptor/Ligand Binding and Trafficking Processes; 4. Signal Transduction; 5. Receptor-Mediated Cell Behavior; 6. Future Directions

Write a review

There are currently no reviews for this product. Be the first to review this product!

Bestsellers in this subject

One Plus One Equals One

NHBS Price: £9.99 $13/€12 approx

Ancestral Sequence Reconstruction

NHBS Price: £89.99 $113/€107 approx

The Cell Cycle

NHBS Price: £34.99 $44/€42 approx

The Molecular Life of Plants

NHBS Price: £47.50 $60/€57 approx

The Cyanobacteria

NHBS Price: £215.00 $270/€256 approx