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Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full colour illustrations to facilitate best learning, Laboratory Animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field.
Preface
Preface to the Third Edition
Preface to the Second Edition
Preface to the First Edition
Glossary
List of Tables
List of Figures
Acknowledgements
Introduction
Chapter 1. Basic Principles of Anaesthesia
Introduction: What is Anaesthesia and How Do We Produce it?
Anaesthetic Equipment – Preparation and Use
Intranasal Intubation
Administration of Anaesthetics by Injection
Preparations for Anaesthesia – People and Animals
Anaesthetic Agents
Inhalational Anaesthetic Agents
Injectable Anaesthetic Agents
Selection of Anaesthetic Agents – Scientific and Welfare Considerations
Chapter 2. Managing and Monitoring Anaesthesia
Pre-operative Preparations
Monitoring Anaesthesia
Anaesthetic Problems and Emergencies
Chapter 3. Special Techniques
Use of NMB Agents
Controlled Ventilation
Long-Term Anaesthesia
Anaesthesia of Pregnant Animals
Anaesthesia of Neonates
Anaesthesia for Imaging
Chapter 4. Analgesia and Post-Operative Care
The Recovery Room Environment
Problems During the Recovery Period
Management of Post-Operative Pain
Pain Assessment
Pain Relief
Conclusions
Chapter 5. Anaesthesia of Common Laboratory Species: Special Considerations
Small Rodents
Rabbits
Post-Operative Care
Cats
Dogs
Ferrets
Pigs
Sheep and Goats
Primates
Other Species
Appendix 1. Recommended Techniques and Physiological Data. When No Injectable Anaesthetic Is Recommended, Inhalational Agents Should Be Used
Appendix 2. Estimation of Required Quantities of Volatile Anaesthetics and Anaesthetic Gases
Appendix 3. Examples of Dilutions of Anaesthetic Mixtures for Small Rodents
Rat
Mouse
Guinea-Pig
Birds
Appendix 4. Manufacturers of Equipment and Other Items Illustrated or Cited in the Text
Bibliography
Index
Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group's current research work is focussed on novel methods of "cage-side assessment of pain, particularly using "pain faces and developing methods of measurement of affective state in rodents.
"The preeminent book on laboratory animal anesthesia and analgesia [...] It is easy to locate information in this one-stop resource on laboratory animal anesthesia [...] a well organized book that ensures readers are aware of the most important clinical aspects of a topic. Score: 99 – 5 Stars"
– Doody's
