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Genetics in Wild Mice: Its Application to Biomedical Research

Edited By: M Kazuo, S Toshihiko and Y Hiromichi

334 pages, 96 figs, 41 tabs

S Karger

Hardback | Dec 1994 | #56230 | ISBN: 3805560540
Availability: Usually dispatched within 1-2 months Details
NHBS Price: £264.00 $333/€313 approx

About this book

The house mouse, Mus musculus, is undoubtedly one of the best experimental animals for biomedical research. Because of the similarity between the genetic organization of mice and humans, the mouse is an indispensable tool for genetic approaches to human diseases. However, as classical laboratory strains are highly inbred, polymorphic markers for mapping disease-associated genes are not always available. Wild mice can provide this variation, and can also be used for seeking novel phenotypes for use in biomedical research. Taken together, the contributions to this volume provide an up-to-date review of current knowledge of the genetic profiles of a large variety of wild mice and wild-derived strains.


Contents

Variations and its geographical distribution; immunology; chromosomes and genetic mapping; establishment of wide-derived laboratory strains.

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